Lepra Reactions: Mimickers and Mirror to Unmask Complex Cases of Leprosy

Lepra Reactions: Mimickers and Mirror to Unmask Complex Cases of Leprosy

Blog Article

Leprosy is a silent disease with protean manifestations, especially during lepra reactions (LRs).Cases with atypical leprosy or LR simulate a number of conditions misdiagnosed frequently.Here, three classical cases of leprosy are reported for their complex presentation.Leprosy was hidden in Case 1 due to co-existing Rug diabetes.COVID vaccination induced LR unmasked all leprosy lesions, which were extensive, large, bizarre and spreading to various immune zones.

Case 2 presented with high-grade fever, tachycardia, generalized erythema and body aches.A detailed workup unveiled his leprosy with a rare presentation of Type 1 lepra reaction (T1LR) with erythroderma Playing Cards and severe systemic symptoms.Case 3 mimicked sarcoidosis and lupus erythematosus (LE) on routine workup.She had facial lesions in the malar area, photosensitivity, joint pains, raised angiotensin-converting enzyme (ACE) levels and positive anti-nuclear antibodies.Peri-appendageal granulomas on histopathology and therapeutic response to multidrug therapy helped in the early diagnosis of leprosy.